People with type 1 diabetes are at high risk of developing kidney disease, but no therapies are proven to prevent impaired kidney function in these patients.
Over an average of 22 years in DCCT/EDIC, intensive therapy was more effective at preserving long-term kidney function in study participants. A total of 24 participants assigned to intensive therapy and 46 assigned to conventional therapy developed impaired kidney function, meaning that intensive diabetes therapy reduced patients' risk by 50%. Of those with impaired kidney function, 8 assigned to intensive therapy and 16 assigned to conventional therapy developed kidney failure.
"This study demonstrates that impaired kidney function can be prevented in type 1 diabetes and reinforces the importance of maintaining good glucose control early in the course of type 1 diabetes to prevent long-term kidney complications," said Dr. de Boer.
http://www.sciencedaily.com/releases/2011/11/111112145357.htm
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